Ed Miliband acknowledged that "mistakes" had been made over climate change data but insisted the effect was happening and was "man-made".
At Commons question time, the Energy and Climate Change Secretary disclosed that he had written to Rajendra Pachauri, chairman of the Intergovernmental Panel on Climate Change (IPCC), urging him to eliminate such errors in the future.
His comments came as Dr Pachauri was due to make his case to world leaders in Bali after calls for his resignation in the wake of the discovery of errors in the IPCC's latest report.
The meeting follows publication of hacked emails from University of East Anglia climate change scientists, which sceptics claimed showed they had been manipulating climate data.
Liberal Democrat Evan Harris (Oxford W and Abingdon) said despite the controversy "the science is very clear from other data sets, not least, that global warming is a real effect".
Mr Miliband said: "There have been mistakes made, clearly. It's important in relation to the IPCC that those mistakes are looked at and they look at their procedures.
"I've written to Dr Pachauri to emphasise our support for the organisation but also our wish that they look at their procedures to try and eliminate these sort of errors.
"But the overall picture is very clear, which is that climate change is happening, it is real, it is man-made."
Tory Ann Winterton (Congleton) said: "Recent polls show that the British public has had a dramatic change of mind about whether climate change is man-made.
"Will the Government change its mind about the huge subsidies to land-based windfarms, which are not only ineffective but also despoil the countryside."